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Stress induce brain structure changes

Stress induce brain structure changes : Neurones in the prefrontal cortex, hippocampus,  and amygdala are very responsive to stimuli that can trigger stress and anxiety and these events can reshape the neurones. However, other factors such as the type of stress either physical or psychological or the duration of the stress either acute or chronic affect the extent of reshaping. Other factors include the developmental stage of people whether they are newborn, adolescent, adult, or aged, also their sex and genetic makeup  affect the reshaping. Thus stress affects the structure of neurones in the prefrontal cortex,  hippocampus, and amygdala.

Hippocampus

The hippocampus is very sensitive to a life full of stress. Also, the hippocampus is also involved in processing environmental information and adding them together to make sense in order to avoid being harmed if possible in the nearest future. Chronic stress triggers dendritic withdrawal and reduced branching of neurones and  can trigger spine loss, change in the spine. The dendritic reshaping of  hippocampal neurones can be reversed after a stress-free experience, thus the best way to stay revived in the university, work or any place is to take a time off and relax or stay away from what stresses you.

Stress induce brain structure changes
Stress induce brain structure changes: Neurones in the prefrontal cortex, hippocampus, and amygdala are very responsive to the cause of stress and anxiety . Adapted from Leuner et al., 2013.

The alteration of  dendrites or spines in the hippocampus during stress is made possible by stress-induced  reorganisation of the neuronal cytoskeleton via  structural changes to proteins such as  actin and microtubules. The Scientific result has shown that stress may not so much decrease the density of spines in females compared to males, however, this is modulated by hormonal changes.

Prefrontal cortex

Also, neurones in the prefrontal cortex are very sensitive to stress and undergo reshaping after exposure to stress or triggers and may differ from male to females.  For example in the female, stress increases dendritic branching and length of pyramidal neurones in the medial prefrontal cortex compare to male. However, chronic stress in males leads to dendritic spine loss. Stress alters neuronal structure throughout the medial prefrontal .

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